Machine Learning for Safety-Critical Applications: Opportunities, Challenges, and a Research Agenda
2025

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Advances in artificial intelligence, and specifically in machine learning, are enabling new capabilities across nearly every sector of the economy. Many of these applications - such as automated vehicles, the power grid, or surgical robots - are safety critical: where malfunctions can result in harm to people, the environment, or property. While machine learning is already being deployed to enhance the capabilities of some physical systems, extending the rigorous practices of safety engineering to include machine learning components brings significant challenges.

Machine Learning for Safety-Critical Applications explores ways to safely integrate machine learning into physical systems and presents research priorities for improving safety, testing, and evaluation. This report finds that designing machine learning algorithms in a way that aligns with safety engineering standards will require changes in research, training, and engineering practice - as well as a shift away from focusing on algorithmic performance in isolation.

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106 pages · 8.5 x 11 · paperback
ISBN Paperback: 0-309-72666-2
ISBN Ebook: 0-309-72667-0
DOI: https://doi.org/10.17226/27970

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National Academies of Sciences, Engineering, and Medicine. 2025. Machine Learning for Safety-Critical Applications: Opportunities, Challenges, and a Research Agenda. Washington, DC: The National Academies Press.

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Front Matter i-xii
Summary 1-10
1 Engineering Safety-Critical Systems in the Age of Machine Learning 11-27
2 State of the Art, Promises, and Risks of Machine Learning 28-45
3 System Engineering with Machine Learning Components for Safety-Critical Applications 46-60
4 A Research Agenda to Bridge Machine Learning and Safety Engineering 61-72
5 Societal Considerations to Build Public Understanding and Confidence in Safety-Critical Systems with Machine Learning Components 73-86
Appendix A: Statement of Task 87-88
Appendix B: Briefings to the Committee 89-89
Appendix C: Committee Member Biographical Information 90-94

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Machine Learning for Safety-Critical Applications: Opportunities, Challenges, and a Research Agenda (2025)

Chapter: Appendix B: Briefings to the Committee

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Publication information

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Machine Learning for Safety-Critical Applications: Opportunities, Challenges, and a Research Agenda (2025)

Chapter: Appendix B: Briefings to the Committee