An ad hoc planning committee will plan and conduct a public workshop to examine and discuss genomics-based approaches to repurposing existing or developing therapeutics. The goal of the workshop will be to assess the current landscape of drug repurposing activities in industry, academia, and government; examine enabling tools and technology; evaluate the business models and economic incentives; and advance discussions among a broad array of stakeholders that may include government officials, pharmaceutical company representatives, academic researchers, regulators, funders, and patients. The planning committee will develop the workshop agenda, select and invite speakers and discussants, and moderate the discussions. An individually authored summary of the workshop will be prepared by a designated rapporteur in accordance with institutional policy and procedures.