Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop (2025)
Chapter: Appendix B: Workshop Agenda
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Appendix A: Statement of Task
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Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
B
Workshop Agenda
Convened by the Forum on Traumatic Brain Injury, Forum on Neuroscience and Nervous System Disorders, and Forum on Aging, Disability, and Independence
The Keck Center, 500 Fifth Street, NW
Washington, DC 20001
October 21, 2024
SESSION 1—INTRODUCTION
Objectives
- Highlight the unique challenges of managing TBI in older adults, including factors related to heterogenous clinical phenotypes, the physiology of natural brain aging, polypharmacy, and presence of comorbidities.
- Consider unmet research needs from the first-person lived experience perspective of TBI survivors and advocates.
- Overview what is known about TBI incidence and prevalence in older adults, and discuss opportunities to improve data capture and data sharing in population surveillance.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
| 9:00am |
Welcome and Introductory Remarks
Kristine Yaffe, M.D.—University of California, San Francisco David Reuben, M.D.—University of California, Los Angeles |
| 9:15am |
Why TBI in Older Adults Has Unique Considerations
Kristen Dams-O’Connor, Ph.D.—Icahn School of Medicine at Mt. Sinai |
| 9:35am | Discussion |
| 9:45am |
TBI Recovery and Advocacy—Perspectives on Unmet Needs from Lived Experiences
Cindy Daniel—National Concussion Management Center |
| 10:00am | Discussion |
| 10:10am |
Knowledge Gaps in the Neuroepidemiology of Geriatric TBI
Jeremiah Kinsman, Ph.D.—National Highway Traffic Safety Administration Dana Waltzman, Ph.D.—Centers for Disease Control and Prevention |
| 10:25am | Discussion |
| 10:35am | Break |
SESSION 2—PERSPECTIVES ON ADDRESSING UNMET RESEARCH NEEDS IN ACUTE TBI CARE FOR OLDER ADULTS
Objectives
- Explore unanswered questions to help guide neurocritical care delivery decisions including imaging orders, neuromonitoring, surgery, triage transfers, and the distribution of health system resources.
- Consider priorities in health systems research to improve engagement, education, and consultation with patient–caregiver dyads.
- Examine research gaps in geriatric TBI populations with preexisting cognitive impairment and dementia.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
| 10:50am |
Session Introduction
Hibah Awwad, Ph.D.—National Institute of Neurological Disorders and Stroke |
| 10:55am |
Emergency Medicine in Geriatric TBI: Gaps in Prognostication and the Need for Improved Implementation of Value-Based and Patient-Centered Care
Kevin Biese, Ph.D.—University of North Carolina at Chapel Hill |
| 11:05am |
Neurocritical Care Systems in Geriatric TBI: A Need for Multidisciplinary Teaming in Coordinated Systems of Patient-Centered Care from Triage to Recovery
Neha Dangayach, M.D.—Icahn School of Medicine at Mt. Sinai |
| 11:15am |
Trajectories of Function in the First Year Post-Injury
Raquel Gardner, M.D.—Chaim Sheba Medical Center at Tel HaShomer |
| 11:25am | Discussion |
| 12:00pm | Lunch |
| 1:00pm |
Halftime touchpoint
Rachel Lazarus, Ph.D.—AARP |
SESSION 3—PERSPECTIVES ON ADDRESSING UNMET RESEARCH NEEDS IN POSTACUTE TBI CARE FOR OLDER ADULTS
Objectives
- Consider unaddressed challenges in geriatric TBI care from the perspective of caregivers.
- Explore new approaches to integrate patient priorities and outcome goals into clinical decision making.
- Explore research gaps in understanding how bio-psycho-socio-ecological factors affect outcomes after TBI, highlighting post-TBI dementia as an example.
- Examine knowledge and implementation gaps in postacute care quality and continuity, and consider
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
- research opportunities in home health and outpatient rehabilitation.
- Consider research opportunities to promote healthy brain aging after TBI in older adults given the increased risk of neurologic and vascular disorders.
| 1:15pm |
Session Introduction
Kristine Yaffe, M.D.—University of California, San Francisco |
| 1:20pm |
Qualitative Research on Caregiver Perspectives in Geriatric TBI
Michele Nelson, RN/Ph.D.—University of California, San Francisco |
| 1:35pm |
Care Models for Integrating Patient-Centered and Personalized Goals
Mary Tinetti, M.D.—Yale University |
| 1:45pm |
TBI Among Older Adults and the Social Determinants of Health
Ernest Barthélemy, M.D./M.P.H.—SUNY Downstate Health Sciences University |
| 1:55pm |
Optimizing Care Transitions and Improving Rehabilitative Outcomes
Monique Pappadis, Me.D./Ph.D.—University of Texas, Medical Branch |
| 2:05pm |
Promoting Brain Health After TBI in Older Adults: Lessons Learned from the Epidemiology of Neurologic and Vascular Outcomes
Andrea Schneider, M.D./Ph.D.—University of Pennsylvania |
| 2:20pm | Discussion |
| 2:50pm | Break |
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
SESSION 4—APPROACHES TO REMEDY RESEARCH GAPS AND PROMISING FUTURE DIRECTIONS
Objectives
- Consider ideas on a forward-looking research agenda to improve TBI care and outcomes in older adults, integrating perspectives from neurology, geriatrics, preclinical science, emergency medicine, and drug development.
- Explore the use of digital tools and wearable technologies to predict and prevent falls in older adults.
- Discuss strategies for improving the inclusion of older adults in TBI clinical trials, such as revisiting exclusion criteria and increasing accessibility via remote assessments.
- Examine promising future directions, including the use of at-home monitoring, AI-enabled tools, biomarkers, and personalized care models to better predict, prevent, and treat TBI in older adults.
- Foster discussions on how to translate current research findings into actionable clinical guidelines and health care system reforms to improve TBI care delivery for the aging population.
| 3:10pm |
Session Introduction
Lisa Barnes, Ph.D.—National Institute on Aging |
| 3:15pm |
Innovative Approaches to TBI Prevention in Older Adults
David Ganz, M.D./Ph.D.—University of California, Los Angeles |
| 3:25pm |
Using Digital Technologies to Improve Geriatric TBI Prevention, Research and Care
Jeffrey Kaye, M.D.—Oregon Health & Science University |
| 3:35pm |
Approaches to Increase Inclusion of Older Adults in Clinical Trials and Datasets
Laurie Ryan, Ph.D.—National Institute on Aging |
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
| 3:45pm |
Effect of Age and Time Since Injury on TBI Biomarkers in Older Adults
Frederick Korley, M.D./Ph.D.—University of Michigan |
| 3:55pm |
Needs and Opportunities in Preclinical Research
Janna Harris, Ph.D.—Jackson Laboratory |
| 4:05pm |
Needs and Opportunities in Therapies Development
Ramon Diaz-Arrastia, M.D./Ph.D.—University of Pennsylvania |
| 4:15pm | Discussion |
CONCLUSION
| 4:45pm |
Closing Remarks by Workshop Cochairs
Kristine Yaffe, M.D.—University of California, San Francisco David Reuben, M.D.—University of California, Los Angeles |
| 5:00pm | Workshop Concludes |
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
Suggested Citation:
"Appendix B: Workshop Agenda." National Academies of Sciences, Engineering, and Medicine. 2025. Approaches to Address Unmet Research Needs in Traumatic Brain Injury Among Older Adults: Proceedings of a Workshop. Washington, DC: The National Academies Press.
doi: 10.17226/29099.
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