AUTHOR INFORMATION

Andrew Bindman is the executive vice president and the chief medical officer for Kaiser Permanente. He is responsible for driving superior quality and equitable health outcomes through the integration of quality innovation, care delivery, data analytics, and research in collaboration with the Permanente Medical Groups. He is also Kaiser Permanente’s executive sponsor for the Kaiser Permanente Bernard J. Tyson School of Medicine. Prior to joining Kaiser Permanente, Dr. Bindman spent more than 30 years on the faculty at the University of California, San Francisco (UCSF), where he practiced and taught internal medicine while conducting research on health access and outcomes that resulted in more than 200 published scientific articles. He also served as the director of the Agency for Healthcare Research and Quality in 2016–2017. Dr. Bindman is a graduate of Harvard College and the Icahn School of Medicine at Mount Sinai. A board-certified general internist, he completed his residency in internal medicine at UCSF and was a Robert Wood Johnson Foundation Clinical Scholar at Stanford University. He is an elected member of the National Academy of Medicine and the Association of American Physicians. (Conflict and Interest Disclosures: None)

Grace Cordovano is nationally recognized as a leading patient voice in realms of health equity, techquity, and patients’ rights and governance of artificial intelligence (AI). Upon recognizing significant unmet needs and challenges in patients’ experiences throughout their cancer diagnosis, Dr. Cordovano founded Enlightening Results in 2010. Dr. Cordovano is dedicated to fostering personalized patient advocacy services, specializing in oncology, rare, and catastrophic cases. She has been likened to the “House” of patient navigation, internationally recognized for “navigating the unnavigable.” She strategically guides patients and their care partners through survivorship or end-of-life care planning with empathy, ensuring individuals are armed with the most pertinent, medically credible, easy-to-understand information, tools, and technology to make informed decisions about

their care. Dr. Cordovano is a champion for palliative care, digital health, clinical trials, and harnessing the power of AI in navigating life with a cancer diagnosis. She amplifies that patient care strategies must give the competitive advantage to the patient, not their diagnosis. Dr. Cordovano completed her master’s degree and Ph.D. in biochemistry at the Albert Einstein College of Medicine. She is a board-certified patient advocate via the international credentialing of the Patient Advocate Certification Board. (Conflict and Interest Disclosures: None)

Jodi Daniel is a founder and the managing director at Crowell Health Solutions and a partner at Crowell & Moring where she leads the firm’s Digital Health Practice. She provides strategic, legal, and policy advice to health care providers and health plans that are bringing innovation into practice, and to health technology clients navigating the dynamic health regulatory environment. Daniel is a leader in digital health and health data policy. She was the founding director of the Office of Policy in the Office of the National Coordinator for Health IT (ONC) at the Department of Health and Human Services (HHS), where she led the agency’s federal advisory committees and established national health information technology (IT) policy on privacy, security, consumer e-health, telehealth, and safety and oversight. Daniel developed ONC’s regulatory capacity, led the adoption of health IT standards and certification regulations, and advised the Centers for Medicare & Medicaid Services on health IT incentive programs. Prior to her ONC role, Daniel was a key drafter of the original Health Insurance Portability and Accountability Act Privacy and Enforcement Rules and served as HHS’s first senior counsel for health IT. Daniel received a B.A. in economics from Tufts University, an M.P.H. from the Johns Hopkins Bloomberg School of Public Health, and a J.D. from the Georgetown University Law Center. She is currently an assistant professor adjunct at Yale Medical School. (Conflict and Interest Disclosures: None)

Wyatt Decker is UnitedHealth Group’s executive vice president and chief physician. In this role, Dr. Decker serves as the company’s lead ambassador working across the enterprise and externally with key stakeholders to further enable and advance accountable models of care. Dr. Decker previously served as the chief executive officer of Optum Health, UnitedHealth Group’s national integrated care delivery platform. During his nearly 5-year tenure, he played a vital role in building out and accelerating Optum Health’s value-based care delivery capabilities and helping more than 100,000 employed and contracted physicians achieve lower costs and deliver better outcomes for more than 100 million people, including the nearly 4 million people Optum now serves in fully accountable,

value-based arrangements. Under his leadership, Optum Health established national platforms for care delivery, home and community care, behavioral care, benefits, chronic disease management solutions, and the Center for Advanced Clinical Solutions, applying cutting-edge technologies to solve some of health care’s toughest problems. Dr. Decker holds an M.D. from the Mayo Clinic Alix School of Medicine, an M.B.A. from the Kellogg School of Management at Northwestern University, and a B.S. from the University of California, Santa Cruz. He has published numerous scientific articles and is recognized among the nation’s top 100 health care leaders by Modern Healthcare. (Conflict and Interest Disclosures: None)

Peter J. Embí is an internationally recognized researcher, educator, and leader in the field of biomedical informatics, with particular emphasis in clinical and translational research informatics and the effective and ethical application of artificial intelligence in health care. Dr. Embí serves as a professor and the chair of the Department of Biomedical Informatics, a professor of medicine, the co-director of the ADVANCE AI Center, and the senior vice-president for research and innovation at the Vanderbilt University Medical Center (VUMC). Prior to joining VUMC, he served as the president and the chief executive officer of the Regenstrief Institute, a professor and the associate dean for informatics and health services research at the Indiana University (IU) School of Medicine, the associate director at Indiana Clinical and Translational Sciences Institute, the vice president for Learning Health Systems at IU Health, and on the faculty of the University of Cincinnati (UC), where he was the founding director of the UC Center for Health Informatics. Among his other leadership roles, he is the president of the American College of Medical Informatics (ACMI), was the past president and the chair of the Board of Directors of the American Medical Informatics Association, served on the Board of Scientific Counselors to the National Library of Medicine and on the National Advisory Council for the Agency for Healthcare Research and Quality. He is a fellow of the American College of Physicians, a fellow of the ACMI, a fellow of the International Academy of Health Sciences Informatics, and an elected member of the National Academy of Medicine. (Conflict and Interest Disclosures: None)

Gianrico Farrugia is the president and the chief executive officer of the Mayo Clinic. With a distinct focus on advancing patient-centered health care transformation for the health care sector, Dr. Farrugia is a pioneering voice in moving health care from a linear pipeline operating model to a platform-based model. Under his leadership, the Mayo Clinic launched and scaled Mayo Clinic

Platform, which brings together data partners, solution developers, and health care providers to transform care through insights derived from the world’s most comprehensive repository of longitudinal de-identified clinical data across four continents. To further enable transformation, Dr. Farrugia and his leadership team are re-architecting Mayo Clinic’s physical infrastructure to support the future of care. These efforts include Mayo Clinic’s more than $9 billion investment to invent a new integrated health care experience. This transformation includes bringing the first carbon ion therapy program in the Americas to the Mayo Clinic and advanced biomanufacturing capabilities to all Mayo Clinic destination medical center sites, among other advances. Dr. Farrugia has been a Mayo Clinic physician for more than 35 years. He is jointly appointed in the Division of Gastroenterology and Hepatology, the Department of Internal Medicine, and the Department of Physiology and Biomedical Engineering. He is also a professor of medicine and physiology at the Mayo Clinic College of Medicine and Science. He completed his undergraduate training at St. Aloysius College and earned his medical degree from the University of Malta Medical School. (Conflict and Interest Disclosures: None)

Kadija Ferryman is an anthropologist who studies equity, ethics, and policy in health risk technologies. Dr. Ferryman is faculty at the Berman Institute of Bioethics and assistant professor in the Department of Health Policy and Management at the Johns Hopkins Bloomberg School of Public Health. Before her training as an anthropologist, Dr. Ferryman began her professional career as a policy researcher at the Urban Institute in Washington, DC. She has published in journals such as JAMA, the New England Journal of Medicine, the American Journal of Bioethics, and the Journal of the American Informatics Association. Dr. Ferryman received her B.A. in anthropology from Yale University and her Ph.D. in anthropology from the New School for Social Research. (Conflict and Interest Disclosures: Member, Institutional Review Board, All of Us Research Program, National Institutes of Health; Member, Digital Ethics Advisory Panel, Merck KGaA [Merck Germany])

Sanjay Gupta is the multiple Emmy® Award–winning chief medical correspondent for CNN and host of the CNN podcast “Chasing Life.” Dr. Gupta, a practicing neurosurgeon, plays an integral role in CNN’s reporting on health and medical news for all CNN shows domestically and internationally, and regularly contributes to CNN Digital. Since 2001, Dr. Gupta has covered some of the most important health stories in the United States and around the world. On March 9, 2020, Dr. Gupta penned an op-ed announcing the network would refer

to the novel coronavirus outbreak as a “pandemic,” ahead of the World Health Organization and the Centers for Disease Control and Prevention. Throughout 2020 into 2021, Dr. Gupta reaffirmed his role as a trusted guide to viewers worldwide on navigating between facts and fiction surrounding COVID-19 and the pandemic. In addition to his work for CNN, Dr. Gupta is an associate professor of neurosurgery at Emory University Hospital and the associate chief of neurosurgery at Grady Memorial Hospital in Atlanta. He serves as a diplomat of the American Board of Neurosurgery. In 2019, Dr. Gupta was elected to the National Academy of Medicine. His upcoming book, It Doesn’t Have to Hurt: Your Smart Guide to a Pain-Free Life, will be published in September 2025 with Simon & Schuster. Dr. Gupta received his undergraduate degree from the University of Michigan and M.D. from the University of Michigan Medical School. (Conflict and Interest Disclosures: None)

Eric Horvitz serves as Microsoft’s chief scientific officer, guiding strategic scientific initiatives companywide. He serves on the National Institutes of Health’s (NIH’s) Advisory Committee to the Director working group on artificial intelligence (AI) and previously served on the President’s Council of Advisors on Science and Technology, co-leading studies in health care and biosciences. Dr. Horvitz has also served on the Board of Regents of the National Library of Medicine, as commissioner on the National Security Commission on AI, and as the president of the Association for the Advancement of AI (AAAI). Dr. Horvitz’s research and contributions span machine learning (ML), reasoning, and human–AI interaction. For decades, he has advanced AI applications in health care settings, including harnessing ML to develop and field diagnostic and predictive models. His foundational contributions in AI include probabilistic and decision-theoretic reasoning, models of bounded rationality, and human–AI complementarity and coordination. His honors include the Feigenbaum Prize and the Allen Newell Prize for his contributions in AI; induction into the CHI Academy for advances in human–AI collaboration; election as a member of the National Academy of Engineering, the American Academy of Arts & Sciences, and the American Philosophical Society; and as a fellow of AAAI, the Association for Computing Machinery, the Association for the Advancement of Science, and the American College of Medical Informatics. He co-founded the Partnership on AI and Stanford’s One Hundred Year Study on AI. At Microsoft, he established the Aether Committee, advising on AI safety, trustworthiness, and ethics, and co-founded the Office of Responsible AI, overseeing policies and compliance across company products and services. (Conflict and Interest Disclosures: Employment by Microsoft Corporation; Member, NIH Advisory Committee to the Director Working Group on AI)

Roy Jakobs is the chief executive officer (CEO) of Royal Philips. As the CEO, he is also chair of the Board of Management and the Executive Committee. With his extensive global executive leadership experience, Jakobs drives Philips’s strategy to help deliver better care for more people. He is committed to helping health care professionals provide better care in hospitals, clinics, and the home and empowering people to take care of their health and well-being. His track record over the past 25 years reflects his passion to help address wider societal challenges. He has driven (digital) transformations in energy, scientific information publishing, and health technology in multinational companies. In doing so, he has built high-performing teams, leveraged digital innovation and mergers and acquisitions in business-to-business, business-to-consumer, and business-to-government segments to create value for multiple stakeholders, including patients, customers, and society. Jakobs has an M.B.A. from Radboud University Nijmegen and the Università degli Studi di Bologna, Italy. He also has a master’s degree in marketing from the TIAS School for Business and Society and completed the New Board Program from Nyenrode Business University, both in the Netherlands. (Conflict and Interest Disclosures: None)

Kevin B. Johnson is the David L. Cohen University Professor of Biomedical Informatics, Computer Science, Pediatrics, and Science Communication at the University of Pennsylvania, and the vice president of applied clinical informatics in the University of Pennsylvania Health System. He received his M.D. from Johns Hopkins University and his M.S. in medical informatics from Stanford University. Dr. Johnson is an internationally respected expert in clinical informatics. His current research focuses on clinical documentation and artificial intelligence. Dr. Johnson was among the world’s first researchers to propose and demonstrate the value of text messaging in behavior change. Previously, he served as the chair of the Department of Biomedical Informatics and the chief informatics officer for the Vanderbilt University Medical Center. Dr. Johnson holds numerous national leadership positions and serves on various advisory boards. Dr. Johnson is passionate about educating lay audiences about informatics. He has produced documentaries related to health information technology. His podcast “Informatics in the Round” features experts discussing informatics topics to songwriters. Most recently, he co-published a book series called Who, Me? featuring scientists from marginalized groups, encouraging young children to consider careers in science, technology, engineering, mathematics, and medicine. He has authored more than 200 publications and has won numerous national awards. He was elected to the American College of Medical Informatics in 2004 and the Academic Pediatric Society in 2010, the National Academy of Medicine in 2010, the International

Association of Health Science Informatics in 2021, and the American Institute of Medical and Biological Engineering in 2022.(Conflict and Interest Disclosures: Member, National Scientific Advisory Board, University of Nebraska, Child Health Research Institute; National Advisory Committee Member, Robert Wood Johnson Foundation; Scientific Advisory Board, University of Michigan Taubman Institute; External Advisory Board, Washington University School of Medicine, Institute of Informatics; JAMA Health Forum Editorial Board; Past President, American College of Medical Informatics)

Peter Lee is the president of Microsoft Research. He leads Microsoft Research across its 11 worldwide laboratories to advance human knowledge and incubate research-powered products in artificial intelligence (AI), computer science, health, and life sciences. Before joining Microsoft in 2010, he established a new technology office at the Defense Advanced Research Projects Agency, creating operational capabilities in machine learning, data science, and computational social science. Prior to that, he was a professor and the head of the Computer Science Department at Carnegie Mellon University. Dr. Lee is a member of the National Academy of Medicine and serves on the boards of several institutions in AI and medicine, including the Board of Trustees of the Mayo Clinic and the Boards of Directors of the Kaiser Permanente School of Medicine and the Brotman Baty Institute for Precision Medicine. He served on President Obama’s Commission on Enhancing National Cybersecurity and has testified before both the U.S. House Science and Technology and the U.S. Senate Commerce Committees. With Carey Goldberg and Dr. Isaac Kohane, he is the co-author of the book The AI Revolution in Medicine: GPT-4 and Beyond. In 2024, Dr. Lee was named by Time magazine as one of the 100 most influential people in health and life sciences. (Conflict and Interest Disclosures: Employment by Microsoft Corporation)

Kenneth Mandl directs the Computational Health Informatics Program at Boston Children’s Hospital and is the Donald A.B. Lindberg Professor of Pediatrics and Biomedical Informatics at Harvard Medical School. He is trained as a pediatrician and pediatric emergency physician. Dr. Mandl is a member of the National Academy of Medicine and as part of its Leadership Consortium, co-chairs its Digital Health and AI Action Collaborative. He has had a sustained influence on the field of biomedical informatics, innovating in biosurveillance, federated data sharing, patient control of data, and health care interoperability. Dr. Mandl’s advancements in SMART programming interfaces, in conjunction with his influence on the 21st Century Cures Act, have streamlined universal access to

individual and population health data. These capabilities enhance interoperability in health care systems and foster substantial economies of scale. He leads, across seven children’s hospitals, the Genomic Information Commons and directs the PrecisionLink Biobank for Health Discovery at Boston Children’s Hospital. Dr. Mandl was elected to the American Society for Clinical Investigation, the Society for Pediatric Research, the American College of Medical Informatics, and the American Pediatric Society. He is a recipient of the Presidential Early Career Award for Scientists and Engineers, the Donald A.B. Lindberg Award for Innovation in Informatics, and the Clifford A. Barger Award for top mentors at Harvard Medical School. He was the advisor to two directors of the Centers for Disease Control and Prevention and chaired the Board of Scientific Counselors of the National Institutes of Health’s National Library of Medicine. (Conflict and Interest Disclosures: Boston Children’s Hospital receives philanthropic contributions on behalf of Dr. Mandl’s laboratory from the SMART Advisory Committee with members including Cambia, Humana, HCA Healthcare, and BMJ Group. Equity in SMART Check-In.)

Kedar Mate is the chief medical officer and the co-founder of Qualified Health. He is the former president and chief executive officer of the Institute for Healthcare Improvement (IHI), a global organization advancing equitable health outcomes through improvement science. With more than 20 years of experience in health care management, public health, and quality improvement, he champions innovative approaches to enhance global health. Dr. Mate co-hosts the “Turn On The Lights” podcast, where he delves into the intersection of health, social justice, and leadership with a diverse array of inspiring guests. He also co-leads the Rise to Health Coalition, a national health equity initiative by IHI, the American Medical Association, and Race Forward. Dr. Mate is passionate about creating systems that address social determinants of health, foster collaboration and learning, and promote innovation and excellence. (Conflict and Interest Disclosures: Co-founder and chief medical officer of a generative AI health care company, Qualified Health)

Deven McGraw is the chief regulatory and privacy officer for Citizen Health, a platform for patients to gather, manage, and share their complete health histories (previously known as Ciitizen and recently divested from Invitae). From 2015–2017, she directed U.S. health privacy and security as the deputy director of health information privacy at the Department of Health and Human Services’ Office for Civil Rights and as the chief privacy officer (acting) of the Office of the National Coordinator for Health Information Technology. Widely recognized

for her expertise in health privacy, she directed the Health Privacy Project at the Center for Democracy & Technology for 6 years, testifying before Congress on health privacy issues on multiple occasions. She currently serves on the federal Health Information Technology Advisory Committee, the Steering Committee for Carequality, the California Data Sharing Agreement Policies and Procedures Subcommittee, and the Data and Surveillance Workgroup of the Center for Disease Control and Prevention’s (CDC’s) Advisory Committee to the director on CDC’s Data Modernization Initiative. She also is on the board of Manifest MedEx, the largest health information exchange in California. She previously was the chief operating officer of the National Partnership for Women and Families and, before joining federal government service, advised health industry clients on Health Insurance Portability and Accountability Act compliance and data governance while a partner at Manatt, Phelps & Phillips, LLP. McGraw graduated magna cum laude from Georgetown University Law Center and has an M.P.H. from the Johns Hopkins Bloomberg School of Public Health. (Conflict and Interest Disclosures: Employment and minority shareholder interest in Citizen Health, Inc.)

Bakul Patel is the senior director of global digital health strategy and regulatory at Google, focused on building a unified digital health strategy that is aligned with evolving global regulatory needs. Patel’s vision is to help realize the potential of technology and its role in democratizing access to high-quality, equitable health care. Prior to joining Google, Patel held the position of the chief digital health officer of global strategy and innovation and the founding director for the Digital Health Center of Excellence at the U.S. Food and Drug Administration (FDA). In these roles, he provided thought leadership and expertise and shaped responsible regulation that balanced innovation and patient safety for digital health. Patel coined the term “software as a medical device” and authored a risk framework and playbook that is now adopted by many medical device regulators globally. He was also the architect of the software precertification pilot program and FDA’s framework for artificial intelligence/machine learning–based software that created the predetermined change control plan novel approach for FDA. Patel earned an M.S. in electronic systems engineering from the University of Regina, Canada, and an M.B.A. in international business from Johns Hopkins University. (Conflict and Interest Disclosures: Employment by Google, LLC)

Philip Payne serves as the chief health artificial intelligence (AI) officer for BJC Healthcare and Washington University Medicine and he is the founding

director of their joint Center for Health AI. He also holds the Janet and Bernard Becker Professorship and is the founding director of the Institute for Informatics, Data Science, and Biostatistics at the Washington University School of Medicine. Additionally, Dr. Payne is a professor of general internal medicine and computer science and engineering. With more than 300 publications, he leads a dynamic research group that addresses areas such as (1) AI-driven methods for discovering and analyzing biomolecular and clinical phenotypes, (2) interventional applications of electronic health records and clinical decision support, (3) human factors and workflow optimization in health care information technology, and (4) the development and assessment of data sharing and analytics platforms to support high-value, agile health care systems and research initiatives. Dr. Payne is an elected fellow of the American College of Medical Informatics, the American Medical Informatics Association (AMIA), the American Institute for Medical and Biological Engineering, and the International Academy of Health Sciences Informatics. He currently serves as the president-elect of AMIA, the leading professional organization in biomedical and health informatics. Beyond academia, Dr. Payne is an active entrepreneur, founding multiple digital health companies and serving in advisory and governance roles with various health and life sciences companies and venture capital firms. (Conflict and Interest Disclosures: None)

Vardit Ravitsky is the president and chief executive officer of the Hastings Center, an independent, non-partisan bioethics research institute that is among the most prestigious bioethics and health policy institutes in the world. She is a senior lecturer on global health and social medicine at Harvard Medical School, and was a full professor at the Bioethics Program, School of Public Health, University of Montreal. She is the past-president of the International Association of Bioethics and a fellow of the Canadian Academy of Health Sciences and of The Hastings Center. Dr. Ravitsky’s research focuses on the ethics of genomics and reproduction and the use of artificial intelligence in biomedical research. It is funded by Canada’s leading funding agencies and the National Institutes of Health (NIH). She has published more than 200 articles and commentaries on bioethical issues and given more than 300 talks worldwide and more than 400 media interviews. Dr. Ravitsky holds a B.A. from the Sorbonne University in Paris, an M.A. from the University of New Mexico in the United States, and a Ph.D. from Bar-Ilan University in Israel. Previously, she was a fellow in the Department of Bioethics at NIH and faculty at the Department of Medical Ethics, School of Medicine, University of Pennsylvania. She was also a senior policy advisor at the Canadian Institutes of Health Research’s Ethics Office and a GE3LS (genomics

and its ethical, economic, environmental, legal, and social implications) consultant to Genome Canada. (Conflict and Interest Disclosures: None)

Suchi Saria holds a John C. Malone endowed chair and is the director of the Machine Learning and Healthcare Lab at Johns Hopkins University, where she is jointly appointed as faculty in computer science, medicine, and health policy. She is also the founder of Bayesian Health, a clinical artificial intelligence (AI) platform company spun out of Johns Hopkins that augments care teams by bringing together the state of the AI and machine learning (ML) technology combined with responsible AI best practices to dramatically improve quality while saving clinicians’ time. Dr. Saria’s work in AI over the past two decades has led to foundational advances in the technology, best practices around translation, and AI policy. She has written several seminal papers in AI/ML around issues of learning robust models, detecting drifts, and monitoring and learning from messy real-world datasets. Her applied research has built on these technical advances to develop novel next-generation diagnostic and treatment planning tools that use AI/ML to individualize care. Her work has been funded by leading organizations including the National Science Foundation, the Defense Advanced Research Projects Agency, the U.S. Food and Drug Administration, the National Institutes of Health, and the Centers for Disease Control and Prevention and she regularly serves as a scientific advisor to leading Fortune 500 companies. Dr. Saria completed her Ph.D. in AI at Stanford University. In 2024, she received an honorary doctorate from Mount Holyoke. She is a Sloan Research Fellow, named by the Institute of Electrical and Electronics Engineers to “AI’s 10 to Watch,” Modern Healthcare’s Top 25 Innovators, World Technology Forum’s Technology Pioneer, and her work was recognized as one of Time Magazine’s Best Inventions in 2023 and 2024. (Conflict and Interest Disclosures: Stock for scientific and technical work in Bayesian Health, Duality Tech, Century Health, Midstream Health, and Latent; Grant/Research support from the National Science Foundation, National Institutes of Health, and Food and Drug Administration)

Eric Topol is the executive vice-president of Scripps Research, the largest non-profit biomedical research institution in the United States, where he was the founder and directs the Scripps Research Translational Institute as the chair and a professor of translational medicine. He has published more than 1,300 peer-reviewed articles, with more than 370,000 citations. He was elected to the National Academy of Medicine and is one of the top 10 most cited researchers in medicine. His research is dedicated to promoting human health using genomic, digital and artificial intelligence. He authored three best-seller books on the

future of medicine: The Creative Destruction of Medicine, The Patient Will See You Now, and Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again. His new book is Super Agers: An Evidence-Based Approach to Longevity. Dr. Topol is the principal investigator to two large National Institutes of Health grants, the All of Us Research Program that supports precision medicine and a Clinical and Translational Science Award that promotes innovation in medicine. He was the founder of a new medical school at Cleveland Clinic (Lerner College of Medicine), was commissioned by the United Kingdom to lead a review of its National Health Service, and is active clinically as a cardiologist. At Substack, he publishes “Ground Truths,” a weekly newsletter and podcast on cutting-edge biomedical advances. (Conflict and Interest Disclosures: Advisor to Abridge, Tempus Labs, and Pheno.ai)

Selwyn Vickers is the president and chief executive officer (CEO) of Memorial Sloan Kettering Cancer Center (MSK) and the director of the MSK Comprehensive Cancer Center. He is a world-renowned surgeon, pancreatic cancer researcher, and pioneer in health disparities research. His major research interests include gene therapy as an application in the treatment of pancreatobiliary tumors, the role of growth factors and receptors in the oncogenesis of pancreatic cancer, the implications of FAS expressions and Tamoxifen in the growth and treatment of cholangiocarcinoma, assessment of clinical outcomes in the surgical treatment of pancreatobiliary tumors, and the role of death receptors in the treatment of pancreatic cancer. Dr. Vickers is a member of the National Academy of Medicine (NAM), a fellow of the American Association for Cancer Research, and an honorary member of the American Society for Clinical Investigation. He is a member of more than 22 professional societies and has held leadership roles in many, including the NAM, the American Surgical Association, and the Society of Black Academic Surgeons. He has more than 270 peer-reviewed publications spanning 25 years of National Institutes of Health funding investigating the molecular basis for pancreatic adenocarcinoma, developing novel therapeutic approaches, and understanding disparities in cancer incidence, access to care, and clinical trial enrollment. Dr. Vickers has held several academic leadership roles, including the chair of the Department of Surgery at the University of Minnesota Medical School, the dean and the senior vice president of the Heersink School of Medicine at the University of Alabama at Birmingham (UAB), and CEO of the UAB Health Systems and CEO of the UAB/Ascension St. Vincent’s Alliance. (Conflict and Interest Disclosures: None)

EDITOR INFORMATION

Laura Adams is a senior advisor at the National Academy of Medicine (NAM). She provides strategic counsel and leadership for the Science and Technology portfolio of the NAM Leadership Consortium and its initiatives on the digital infrastructure and accelerated use of artificial intelligence (AI) in health, health care, and biomedical science. She leads the NAM’s AI Code of Conduct (AICC) national initiative and her expertise is in AI, digital health, and human-centered care. Adams is a member of the international AI Expert Panel for the Organisation of Economic Co-operation and Development, the Bipartisan Policy Center’s Health Care AI Advisory Panel, and the Consumer Technology Association’s Health AI Planning Council. Adams chairs the Global Opportunities Group for The Centre of Excellence for AI Regulatory Science and Innovation in the United Kingdom. She is a strategic advisor for Maverick Health Policy in Washington, DC, and Inflammatix, a Burlingame, California-based biotech company specializing in host immune response diagnostics. Prior to her work at the NAM, Adams was the founding president and chief executive officer of the Rhode Island Quality Institute, Rhode Island’s statewide health information exchange. (Conflict and Interest Disclosures: Board member, TMA Precision Health; Strategic Advisor, Inflammatix; Strategic Advisor, Maverick Health Policy)

Elaine Fontaine currently serves as a special advisor to the Science and Technology portfolio of the Leadership Consortium at the National Academy of Medicine. With more than 30 years of senior leadership experience in health information technology across provider, payer, research, and health information exchange sectors, she is recognized for translating emerging technologies into practical, real-world solutions. Prior to her consulting role, she was the chief operating officer at the Rhode Island Quality Institute (RIQI), overseeing operations in finance, information technology, analytics, compliance, contracting, human resources, sales, and grant management. During her tenure, RIQI received several notable accolades, including the 2017 Innovation Award in Healthcare in Rhode Island, the 2018 national Healthcare Informatics Innovation Award for its impact on the opioid crisis, and recognition as a finalist for the 2018 New England Business Innovation Award. Fontaine has also co-authored multiple peer-reviewed publications and presented her work at both local and national technology and analytics forums. (Conflict and Interest Disclosures: None)

Sunita Krishnan serves as a senior program officer on the National Academy of Medicine’s (NAM) Leadership Consortium team. Krishnan leads the Science

and Technology portfolio, which houses the Digital Health and AI Action Collaborative and the Evidence and Data Action Collaborative. In addition, she serves as the project manager for the AI Code of Conduct project. Prior to joining the NAM, Krishnan served as a senior manager at AcademyHealth. She managed the day-to-day activities of the Evidence-Informed State Health Policy Institute that aims to increase the use of relevant, timely, and translatable evidence in state policymaking to improve health and health care quality, outcomes, equity, accessibility, and affordability. Prior to joining AcademyHealth, Krishnan worked as a health policy research assistant for the Healthcare Value Hub, where she wrote research reports on various health value and quality topics, such as telehealth, patient-shared decision making, pharmaceutical costs, and more. She also worked at the American Association for Retired Persons (AARP) as a legislative fellow where she provided research support on state legislation pertaining to long-term care and logistical support for meetings. Krishnan graduated with a B.S. in biology and public health from the University of Minnesota and received her M.P.H. specializing in health policy from The George Washington University. (Conflict and Interest Disclosures: None)

Michael Matheny is the director for the Center for Improving the Public’s Health with Informatics and a professor in the Departments of Biomedical Informatics, Medicine, and Biostatistics at the Vanderbilt University Medical Center. He is also a part-time primary care physician, physician scientist, board certified in internal medicine and clinical informatics, and the associate director of health systems research and development in the VA Informatics and Computing Infrastructure at the Tennessee Valley Healthcare System VA in Nashville, Tennessee. He is an elected fellow of the American College of Medical Informatics, an elected fellow of the American Medical Informatics Association, and an elected member of the American Society of Clinical Investigation. Dr. Matheny’s work has focused on developing and adapting artificial intelligence and machine learning methods for medical product active surveillance, algorithm vigilance, probabilistic phenotyping, natural language processing, and risk prediction modeling. (Conflict and Interest Disclosures: None)

CONTRIBUTOR INFORMATION

David Dorr is an internal medicine doctor and the chief research information officer at Oregon Health & Science University (OHSU). He focuses on improving capabilities and the use of innovations to manage data, information, and knowledge in research and in translating it to health care. He earned his

bachelor’s degree in economics (with minors in mathematics and psychology) and his M.D. from Washington University in St. Louis. He then completed his internal medicine residency at OHSU and earned a master’s degree in medical informatics and health services administration from the University of Utah. Broadly, Dr. Dorr’s interests lie in complex care management, especially for older adults and other at-risk populations, coordination of care, collaborative care, chronic disease management, quality, and the requirements of clinical information systems to support these areas. From these interests, he has broadened into clinical information needs, electronic health record deployment and health information exchange as a way to expand systems-based approaches to all of health care. Finally, Dr. Dorr performs evaluations of care management and informatics initiatives using a variety of methodologies. (Conflict and Interest Disclosures: None)

Andrea Downing is a security researcher and advocate. She has expressed significant concerns about health privacy, particularly in the context of online patient communities and the use of social media for support groups. Her work emphasizes the vulnerabilities and risks associated with the sharing and handling of sensitive health information in digital spaces. Downing’s advocacy is rooted in her personal journey as a BRCA1 mutation “previvor,” which has driven her to focus on privacy protection within the breast cancer community. She co-founded The Light Collective, aiming to create safe spaces on the Internet where individuals can share their experiences and receive support without compromising their privacy. (Conflict and Interest Disclosures: Board President of The Light Collective)

Tyler Loftus is a trauma and acute care surgeon and an intensive care unit doctor in the University of Florida Department of Surgery. He treats patients for traumatic injury and those needing emergency general surgery. He is passionate about resident education and professional development and serves as the program director for the University of Florida General Surgery residency. His National Institutes of Health–funded research pursuits have evolved from translational science, focusing on bone marrow failure and anemia after traumatic injury, to data science, focusing on machine learning to augment personalized, patient-centered decision making. (Conflict and Interest Disclosures: None)

Shauna Overgaard works to advance the safe, effective, and equitable integration of artificial intelligence (AI) into clinical practice through the development of enterprise frameworks for evaluation, implementation, and oversight. Her efforts

center on aligning innovation with regulatory science, implementation science, and clinical usability to ensure AI technologies meet the highest standards of patient care and accelerate innovation to practice. Dr. Overgaard is the senior director of AI strategy and frameworks at the Mayo Clinic and the co-director of the AI Validation & Stewardship Program. Her scholarly work focuses on translational AI governance, clinical assurance, and equitable adoption. She serves on the Editorial Board of npj Health Systems and as a special topics guest editor for BMJ Health & Care Informatics and the Mayo Clinic Proceedings: Digital Health. Dr. Overgaard is recognized as a Rising Star in Modern Healthcare’s 2025 Leading Women in Healthcare. Before her work in AI translation, she was involved in clinical research focused on the development of diagnostic tests leveraging principles of graph theory and multimodal data in the realm of neuroimaging, proteomic, and genomic data. She continues to maintain a responsibility to help facilitate national consensus-building efforts related to medical informatics and health AI. (Conflict and Interest Disclosures: None)

Ravi B. Parikh is an oncologist and an associate professor at Emory University and the Winship Cancer Institute. His research investigates how doctors, patients, and health policy makers can use artificial intelligence (AI) to improve decision making and promote equitable health care. Dr. Parikh’s lab, the Human-Algorithm Collaboration Lab, runs clinical trials testing how clinicians and AI collaborate in making decisions about diagnosis, prognosis, and treatment selection. Dr. Parikh’s work has been published in Science, the New England Journal of Medicine, and JAMA and he has written about AI for The New York Times and The Washington Post. He sits on the Board of the Coalition to Transform Advanced Care. Dr. Parikh graduated from Harvard Medical School and the Kennedy School of Government. He completed his clinical training at Brigham and Women’s Hospital and the University of Pennsylvania. Dr. Parikh has received awards from the National Academy of Medicine, the American Medical Association, the American Society for Clinical Oncology, and the American College of Physicians. (Conflict and Interest Disclosures: Grants from various foundations and other non-commercial organizations for research on AI in health and health care decision making; personal fees and equity from GNS Healthcare, Thyme Care, Main Street Health, and Onc. AI; personal fees from the ConcertAI, Cancer Study Group, Mendel.ai, Optinosis, Biofourmis, Archetype Therapeutics, CreditSuisse, G1 Therapeutics, Humana, and Nanology; honoraria from Flatiron and Medscape; board membership [unpaid] at the Coalition to Transform Advanced Care and American Cancer Society; editor at the Journal of Clinical Oncology; and serves on a leadership consortium [unpaid] at the National Quality Forum, all outside the submitted work)